Welcome to question of the day #50
What are the key steps in the development of rhegmatogenous retinal detachment?
The vitreous humor is a hydrated gel whose structure is maintained by a collagenous and mucopolysaccharide matrix.
As people age, this macromolecular network begins to liquefy and collapse.
The vitreous shrinks, and vitreo-retinal traction develops.
Eventually, the vitreous partly separates from the retinal surface which is known as posterior vitreous detachment.
In 10-15% of patients with symptomatic posterior vitreous detachment, a retinal flap, tear or hole forms as the vitreous pulls away from the retina.
Rhegmatogenous detachment occurs when liquid vitreous enters the subretinal space through a retinal break.
This creates a plane of dissection between the retina and retinal pigment epithelium.
Over time, the area of detachment increases as more fluid passes through the retinal break.